Several studies have shed light on the indisputable effect of structural regulations in reducing the use of cigarettes in both adult and young populations (Rod et al., 2024; Vestbo et al., 2018). It is critical to implement national regulations on new nicotine products, as more youth than ever are using the products at a younger age and international regulations have not addressed these products yet.
Health consequences of nicotine use in childhood and adolescence
Nicotine is a toxic alkaloid originating from the tobacco leaves, where it serves as a defence mechanism against insects and other threats to the tobacco plant. Nicotine is the addictive component in tobacco products and is harmful to the human body (National Center for Chronic Disease Prevention & Health Promotion (US) Office on Smoking and Health, 2014), especially when used in adolescence (Vestbo et al., 2022). First and foremost, nicotine crosses the blood and brain barrier easily, causing neurological and cognitive impairments to the developing brain. This results in negative effects on the maturation of the brain and thus the development of attention, motivation, self-control, and emotional regulation (Jacobsen et al., 2005; Smith et al., 2015; Treur et al., 2015). Additionally, reverse associations between nicotine and mental health have been found, indicating that nicotine might induce symptoms of anxiety and depression (Goodman & Capitman, 2000; Johnson et al., 2000). Nicotine use in adolescence also increases the risk of damage to the oral mucosa and cardiovascular diseases later in life (Miluna-Meldere et al., 2024; National Center for Chronic Disease Prevention & Health Promotion (US) Office on Smoking and Health, 2014; Rungraungrayabkul et al., 2024; Vestbo et al., 2022).
The addiction to nicotine itself also has a negative impact on the everyday life of adolescents, i.e., feeling stuck in their addiction or experiencing that the joy of everyday activities is conditioned by nicotine use (Amato et al., 2021; Mathew et al., 2017; Vestbo et al., 2022). Also, the use of nicotine at a young age increases the risk of lifelong addiction and experimentation with other, potentially more harmful, substances. This is the so-called gateway effect of nicotine use (Yuan et al., 2015).